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Electromagn Biol Med. 2007;26(4):277-81.

Extremely Low Frequency Electromagnetic Fields Prevent Chemotherapy Induced Myelotoxicity

Rossi E, Corsetti MT, Sukkar S, Poggi C.

Side effects of chemo-radiotherapy reduce the quality and also the survivability of patients. The consequent fatigue and infections, related to myelodepression, act to reduce the dose-intensity of the protocol. Late side effects of chemo-radiotherapy include secondary tumours, acute myeloid leukemias and cardiotoxicity. Side effects of chemotherapy are related to oxidative stress produced by the treatment. Oxidative stress also reduces the efficacy of the treatment. Antioxidative treatment with natural (dietetic) or chemical agents has been reported to reduce the toxicity of chemo-radiotherapy and improve the efficacy of treatment. We here report our experience with SEQEX, an electromedical device that generates Extremely Low Frequency ElectroMagnetic Fields (ELF-EMF) to produce endogenic cyclotronic ionic resonance, to reduce myelotoxicity consequent to ABVD protocol in patients with Hodgkin's lymphoma.
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Electromagn Biol Med. 2007;26(4):283-8.

Effects of cyclotronic ion resonance on human metabolic processes: a clinical trial and one case report.

Vallesi G, Raggi F, Rufini S, Gizzi S, Ercolani E, Rossi R.

We studied the effects of ion cyclotron resonance (Seqex) magnetic therapy on the blood of thirty two healthy volunteers. They received 15 treatments each 27 minutes in length, distributed over 5 weeks. The concentrations of two blood components, malondialdehyde (MDA) and cholesterol were measured in each subject, immediately before and immediately after the 15 treatments as well as one month after the final treatment. Highly significant reductions in MDA concentrations, averaging 53.8% were noted just after the 15 treatments, tending to return to the original concentrations one month later. The effect on HDL and LDL cholesterol levels were not significant. The implication of this work is that this type of therapy may be useful in dealing with oxidative stress.
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Electromagn Biol Med. 2007;26(4):299-303.

Cyclotronic ion resonance therapy and arthralgia.

Ciafaloni A.

A total of 143 patients suffering various musculoskeletal disorders including rheumatoid arthritis, arthritis, osteoporosis, and post-surgical discomfort were subjected to ELF magnetic treatments using the Seqex device. A clear trend in pain reduction was observed over the 10 treatment regimen as well as a stabilization of relevant lab tests, including cholesterol level and blood pressure. Improvements were also noted in posturometric footboard tests. An additional 20 patients with various neuromuscular difficulties were treated with Seqex as well as magentic "concentrators" for periods ranging from 3 to 10 treatments. Similar improvements in pain reduction were observed in this smaller group.
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Electromagn Biol Med. 2007;26(4):305-9.

The autistic syndrome and endogenous ion cyclotron resonance: state of the art.

Crescentini F.

The autistic syndrome is a multigenic disease whose expression is different according to the level of involvement of different structures in the central nervous system. The pathogenesis is unknown. No completely effective medical therapy has yet been demonstrated. Accepting the request of the families of eight autistic children in Lomazzo, Milan and Naples, we used ion cyclotron resonance (Seqex therapy) therapeutic support after many other therapies had been already carried out on these patients. After regimens consisting of 20-30 treatments with ICR, improvements were noted in all cases.
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Electromagn Biol Med. 2007;26(4):311-3.

Utilization of extremely low frequency (ELF) magnetic fields in chronic disease; five years experience: three case reports.

Mancuso M, Ghezzi V, Di Fede G.

We present three examples of the use of ELF magnetic therapy, two cases of multiple sclerosis and one of chronic pulmonary disease. In each of the two MS cases the Seqex device was applied as an adjunct to antioxidant medication two times a week for six weeks. Radiological and MRI examination indicated improvement in the two MS patients and stabilization in the patient with obstructive pulmonary disease following merely five treatments.
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Electromagn Biol Med. 2008;27(4):325-39. doi: 10.1080/15368370802493271.

ELF magnetic therapy and oxidative balance.

Raggi F, Vallesi G, Rufini S, Gizzi S, Ercolani E, Rossi R.

Knowledge about the relationship between exposure to extremely low-frequency (ELF) EMF and formation (or neutralization) of free radicals in the living cells is limited. Studies performed on animals and plants have shown conflicting effects on the relation between EMF and oxidative stress. Very few experiments have been performed on humans. The present study reports on the effects of an ELF magnetic therapy device (Seqex) on oxidative scale in humans. This device supplies complex magnetic signals with specific choices of frequency, intensity, and shape that are based on Liboff's ion cyclotron resonance hypothesis. Thirty-two healthy volunteers were treated using the Seqex cycle. A quantitative determination of oxidative stress was obtained at three time points by measuring Malondialdehyde (MDA) concentrations in peripheral blood before and after the cycle and one month following completion of the cycle. A highly significant reduction in mean MDA (53.8%, p = 0.0002) was found at the end of the treatment. One month later the mean MDA had again risen, but there was still a significant overall reduction of 15.6% (p = 0.010) compared to original values.
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Electromagn Biol Med 2007; 26(4):315-25.

Local and holistic electromagnetic therapies.

Liboff AR.

Based on decades of experimental evidence an excellent argument can be made for the existence of a fundamental functional relationship between living systems and electromagnetic fields. We have previously hypothesized that this relationship can be expressed in terms of a field vector whose source is the distribution of electric polarization within the system and which has both a phylogenetic and ontogenetic time dependence. Ion cyclotron resonance (ICR)-like magnetic signals have resulted in physiologic changes in many in vitro and in vivo model systems and have been applied medically with success to bone repair and spinal fusion. This type of local ICR-like therapy has recently been broadened into a holistic application following the remarkable discovery that the whole-body bioimpedance is sharply dependent on ICR signals. We relate this observation to the integrated electric polarization vector, in turn a measure of the double layer charge distribution at the cell membrane. This discovery, already being applied to a number of clinical problems, lends strong support to the concept of an overarching electromagnetic framework for living systems.
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Electromagn Biol Med 2007; 26(4):329-30.

Case study: amyotrophic lateral sclerosis.

Santi C, Turco A

This case report regards the clinical history of a 42 year old man, (Mr. T.) born in Egypt afflicted with motoneuron syndrome, also called ALS (amyotrophic lateral syndrome). An EMG (electromyography) will be done to confirm a change in the clinical situation. The positive clinical response to the cyclotronic ion resonance therapy and the total absence of side effects suggest that we continue the treatment and revise the impedance measurements every two weeks. NO ABSTRACT ON PUBMED
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Electromagn Biol Med 2007; 26(4):293-8.

Effects of endogenous cyclotronic ionic resonance (ICR) on macular diabetic edema: preliminary results.

D'Andrea P, Maurizio L.

The intent in this research was to verify the effects of the application of low frequency magnetic fields to cases of macular diabetic edema. We treated six patients afflicted by non-proliferating diabetic retinopathy with macular oedema. Quantitative clinical appraisals of the retinal thickness were obtained for the Optical Coherence Tomography (OCT I). None of the cases affected by non-cystoid macular oedema (non-CMO), or with a relevant ischemic component, evidenced by retinal fluorangiography, had further worsening in their clinical course during the treatment. Only one of the patients, who underwent a long treatment period with ICR demonstrated a significant reduction of the macular edema, with no need of other invasive therapeutic procedures (intravitreous injection of triamcinolone and/or laser therapy).
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Electromagn Biol Med 2007; 26(4):331.

Case study: peripheric joint disorders.

Castellacci P.

In this preliminary work, 15 patients with valgus and 20 patients with chronic arthritis of the hands (8 patients) and of the feet (12 patients) were studied with clinical examination and radiography. Another 2 patients with tendon-synovitis of the wrist were enrolled. NO ABSTRACT ON PUBMED
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Electromagn Biol Med 2007; 26(4):333-4.

Case study: eosinophilic granuloma.

Campioli GZ.

CASE REPORT. NO ABSTRACT ON PUBMED
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Electromagn Biol Med 2007; 26(4):289-91.

Endogenous cyclotron ion resonance therapy for keratoconus: preliminary results.

Belotti M.

Four keratoconus patients, ranging in age from 24 to 62, and at various stages of the disease, were treated with the combined therapy of low frequency whole body ion cyclotron resonance and magnetic "applicators" applied locally to the temporal area. Following careful examination of the corneal profile using video image acquisition, treatments were given twice a week, for a total of 15 treatments. Following this regimen there were evident morphological changes in several layers of the corneas for all the patients, as well as increased transparency. Despite the limited number of patients in this preliminary study, the positive results suggest a larger follow up study of the effects of ICR treatment for keratoconus.
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